Fresh analysis indicates that people who stop using new weight-loss injections like Wegovy and Mounjaro can put back on shed pounds much more quickly than those who end conventional lifestyle plans.
Research printed in a major health publication points out that while overweight people can lose a large proportion of their body weight while undergoing treatment, the weight returns at an average rate of nearly a kilo each month upon discontinuation.
"People purchasing such treatments need to be cognizant of the danger of quick rebound weight gain when the therapy is stopped," warns researcher Dr. Susan Jebb.
This pace of recovery suggests a return to starting weight within about one and a half years.
Weighing Approaches
The study, which looked at dozens of studies involving over 9,000 of participants, compared the results of GLP-1 agonists with conventional dieting.
Scientists emphasize that people who shed pounds through lifestyle changes alone generally see a less rapid creep back—around 100 grams monthly—post-intervention.
Explaining the Quick Rebound
Doctors propose the mechanism of the jabs is key to understanding the heightened rebound.
These medications copy a body's own chemical called glucagon-like peptide-1, which controls appetite.
"Long-term administration of the hormone concentrations far above than normal may cause the body to generate a reduced amount of its own natural hormone, and could lessen responsiveness to its effects," explained Dr. Adam Collins, a dietetics expert.
"Stopping of this GLP-1 'fix' leads to hunger is no longer kept in check, making overeating much more probable."
A Lifelong Disease?
The NHS suggest the jabs for people with obesity-related medical conditions, alongside recommended lifestyle changes.
A number of clinicians argue that, considering the likelihood of weight regain, the treatment is often long-term.
This opinion is echoed by pharmaceutical companies, who say that the findings "emphasize the chronic character of obesity," similar to managing diseases like diabetes.
Patient Experiences
Individuals who have come off the jabs report a intense resurgence of cravings.
"It was like a trigger flipping and I was suddenly ravenous," described a patient.
This challenge is exacerbated if individuals have not adopted permanent lifestyle or habit modifications during treatment.
Widespread Adoption
Survey data suggest that a significant number of people in the UK have used weight-loss jabs in the last 12 months, with demand remaining high.
- Use is higher among females compared to men.
- The 40s and 50s demographic shows the greatest level of interest.
- Many obtain the medications through private prescriptions rather than the NHS.
In conclusion, researchers stress that while the jabs are powerful tools for weight loss, they are not a magic solution and lasting health benefits hinges on ongoing lifestyle support.
